Noticias sobre VIH/SIDA
Prostate cancer diagnosed later in US men with HIV
Men with HIV in the US’s largest care provider for people with HIV were more likely to be diagnosed late with prostate cancer and less likely to undergo testing that may warn of an increased prostate cancer risk, the Conference on Retroviruses and Opportunistic Infections (CROI 2024) in Denver heard this week.
Categorías: VIH/SIDA
People-centred blood pressure management improves blood pressure in people with HIV
Three studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2024) in Denver this week showed that innovative service models can successfully deliver drug treatment for high blood pressure to people with HIV through HIV clinics or community health workers, and reduce blood pressure.
Categorías: VIH/SIDA
Six-country African PrEP study achieves high levels of persistence and good adherence in young women
A demonstration project of oral PrEP for young women, conducted in six African countries with high HIV prevalence, achieved high levels of PrEP uptake and persistence, and good levels of adherence among its 3000 participants.
Categorías: VIH/SIDA
Islatravir plus lenacapavir could be the first once-weekly oral HIV treatment
A once-weekly oral regimen can keep HIV suppressed as well as daily pills, according to study results presented today at the Conference on Retroviruses and Opportunistic Infections (CROI 2024).
Categorías: VIH/SIDA
Broadly neutralising antibodies may be partners for long-acting antiretrovirals
Two long-acting antiretrovirals, lenacapavir (Sunlenca) and cabotegravir (Vocabria), may pair well with broadly neutralising antibodies for HIV treatment, according to two presentations yesterday at the Conference on Retroviruses and Opportunistic Infections (CROI 2024).
Categorías: VIH/SIDA
HIV diagnoses continue to fall in US states with high PrEP coverage, while others are left behind
The number of new HIV diagnoses has continued to drop steeply between 2012 and 2021 in US states with the highest coverage of PrEP (regular medication to prevent HIV), according to research presented by Dr Patrick Sullivan at the Conference on Retroviruses and Opportunistic Infections (CROI 2024) yesterday.
Categorías: VIH/SIDA
Once-weekly antiretrovirals on the horizon
Two antiretrovirals with the potential for once-weekly oral dosing were unveiled at CROI 2024 in Denver on Monday.
The new agents have undergone phase 1 studies, which establish appropriate dosing and weed out drugs which have serious side effects. Before becoming available for prescription, drugs go through two further phases of testing to establish their efficacy, dosing and safety. During these stages of development many products fall by the wayside either because unexpected problems arise or the commercial priorities of the pharmaceutical company change.
Categorías: VIH/SIDA
If one antibody won’t work, how about three? Or three in one?
This week’s Conference on Retroviruses and Opportunistic Infections (CROI 2024) heard the latest data from research involving giving people a cocktail of three broadly neutralising antibodies (bnAbs), which aidsmap last reported on two years ago.
Categorías: VIH/SIDA
En el Día Internacional de la Mujer, ONUSIDA pide proteger los derechos de las mujeres para proteger su salud
En vísperas del Día Internacional de la Mujer, que se celebra el 8 de marzo, ONUSIDA hace un llamamiento a la protección de los derechos de las mujeres para proteger su salud.
Categorías: VIH/SIDA
Varying dolutegravir distribution across the body may affect the drug’s ability to suppress the HIV reservoir
Analysis of tissue samples from six people with HIV who passed away due to terminal illness revealed varying concentrations of dolutegravir in different body sites and organs. Unsurprisingly, drug concentrations in the brain and the spinal cord were lower than in other body sites, but concentrations across different parts of the brain were evenly distributed. In contrast, the intestines and the spleen – where a large portion of the immune system resides – were found to have high drug concentrations.
Categorías: VIH/SIDA
People need pathways from PEP to PrEP – and back again
Services providing post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP) need to build stronger connections between these two ways of preventing HIV infection, so as to help people who’ve used one method to access the other, according to experts at the Conference on Retroviruses and Opportunistic Infections (CROI 2024).
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Categorías: VIH/SIDA
Sexually transmitted infections in San Francisco have fallen since doxyPEP roll-out
Taking the antibiotic doxycycline after sex appears to have lowered the incidence of sexually transmitted infections (STIs) in San Francisco, according to researchers who presented some of the earliest real-world data yesterday at the Conference on Retroviruses and Opportunistic Infections (CROI 2024).
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Categorías: VIH/SIDA
Full analysis of French STI study dashes hopes for a gonorrhoea vaccine
A year ago, the DoxyVAC study’s interim results raised hopes that by combining post-exposure prophylaxis using the antibiotic doxycycline (‘doxyPEP’) with a candidate vaccine against gonorrhoea, cases of all three of the most important bacterial sexually transmitted infections could be substantially reduced in gay and bisexual men.
Categorías: VIH/SIDA
Injectable treatment just as effective as standard HIV combination in Africa
Injectable treatment with cabotegravir and rilpivirine proved just as effective in maintaining viral suppression as standard oral antiretroviral treatment in a large trial in Africa, despite less intensive viral load monitoring than previous studies, Professor Nicholas Paton of the London School of Hygiene and Tropical Medicine reported at the Conference on Retroviruses and Opportunistic Infections in Denver on Monday.
Categorías: VIH/SIDA
Young people want research to focus on a cure for HIV, sharing their status and U=U
Young people living with HIV in South Africa recently identified their priority research questions as part of an approach which moves away from biomedical research being led by researchers to communities taking the lead. Their priorities were published in PLOS Global Public Health.
Categorías: VIH/SIDA
Statin reduces fat deposits in arteries in people with HIV
As well as lowering levels of harmful cholesterol, statin treatment in people with HIV may cut the risk of heart disease by reducing the size and instability of fat deposits in arteries, according to a sub-study of the REPRIEVE trial published in the journal JAMA Cardiology.
Categorías: VIH/SIDA
Young people living with HIV prefer to learn their status before 12 and from their caregivers
A recent study explored the preferences of adolescent and young adults in Kenya regarding when and how disclosure should happen, along with their satisfaction with the process.
Categorías: VIH/SIDA
Greater weight gain in pregnancy reduces the risk of adverse outcomes for women with HIV
Women with HIV who gained weight during pregnancy after starting dolutegravir-based treatment were less likely to experience birth outcomes such as premature birth, stillbirth or an infant that was small for gestational age, analysis of a large clinical trial has shown.
Weight gained during pregnancy was more likely to be maintained in the year after giving birth by women taking dolutegravir than those taking efavirenz, especially if dolutegravir was taken with tenofovir alafenamide (TAF).
Categorías: VIH/SIDA
En el 10 aniversario del Día de la Cero Discriminación ONUSIDA hace un llamamiento a la protección de los derechos humanos como vía para proteger la salud de toda persona
El Día de la Cero Discriminación fue establecido por ONUSIDA hace diez años para promover la igualdad y la equidad para todas las personas, independientemente del género, la edad, la sexualidad, el origen étnico o el estado serológico respecto al VIH. Sin embargo, los avances están en peligro.
Categorías: VIH/SIDA
Long-acting injectables may be better than daily pills for people with adherence challenges
Antiretroviral treatment using monthly cabotegravir and rilpivirine injections is more effective than daily pills for people who have had difficulty achieving good adherence and maintaining viral suppression, according to an announcement this week from ViiV Healthcare.
Categorías: VIH/SIDA